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The MagLab is funded by the National Science Foundation and the State of Florida.

ICR Science Highlights

Connectivity network derived from protein mass spectrometry data. Individual features are represented as nodes, and links indicate reproducible relationships between them.

June 16, 2026

Protein measurements often produce dense, confusing data that are difficult to interpret. By reorganizing this information into connected patterns, re…


Mass Difference Recalibration Process Diagram

February 10, 2026

MagLab scientists developed a fully automated method to quickly and accurately calibrate extremely complex mass spectra. The technique compares millio…


Figure - created with the assistance of AI-based image generation (OpenAI DALL·E)

November 17, 2025

Scientists need data that’s easy to find, understand, and reuse—both by people and computers. This kind of data is called FAIR, and it’s especially im…


An illustration of the interactions between whales, krill, and phytoplankton in the Southern Ocean under (A) pre-whaling and (B) post-whaling conditions.

October 14, 2025

Whales don’t just eat krill; they help fuel the ocean by releasing a form of iron that the plants of the sea (phytoplankton) can use. They also releas…


Illustration shows the method of detecting molecules in bio-oils

June 13, 2025

This research introduces a new separation method that is combined with precise mass measurements to identify thousands of previously undetected molecu…


Fragments observed after transferring electrons to the protein carbonic anhydrase II.

February 12, 2025

MagLab data collected with the 21 tesla FT-ICR mass spectrometer demonstrate the risk associated with internal fragment annotation in mass spectra of …


(A–D) FT ICR-MS mass spectra of unburned and burned soil from negative-mode electrospray ionization.  ). (E) These m/z ratios were compiled into density plots.

November 14, 2024

Wildfires change the chemical composition of molecules in soil, and only the 21T FT-ICR mass spectrometer can assess the molecular composition to unde…


Gas-phase fragmentation mass spectra (MS/MS) show bad (top right) and good (bottom right) materials for carbon fiber production. Bad materials have many single-core, high-molecular-weight hydrocarbons and sulfur-containing molecules, which don't make stable carbon fibers.

July 16, 2024

MagLab researchers use 21 tesla ion cyclotron resonance (ICR) mass spectrometry to identify the best way to produce carbon fibers from petroleum waste…


Improved mass resolution and signal-to-noise ratio in mass absorption mode mass spectra leads to more assigned chemical formulas within a complex fluid sample.   Reprinted from citation given below. © American Chemical Society.

May 15, 2024

Combining new data with an existing MagLab dataset, researchers characterized the millions of unique chemicals found in our waterways, including both …


Mass spectrum of the initial sample extracted in methanol, with mass-scale zoom inset at m/z 536.

March 27, 2024

The 21T FT-ICR MS instrument enables the molecular characterization of atmospheric hazes - like that on Saturn’s moon, Titan - and water vapor to bett…


Representative DBP molecular formula identifications for a molecule that contains (a) one chlorine atoms. Confident assignment requires the ultrahigh mass resolving power and mass accuracy provided by 21T FT-ICR MS.

November 16, 2023

Identification of toxic compounds in drinking water formed through disinfection reveals more than 3500 toxic, chlorinated species that can only be obs…


Overview of the accessibility needs for scientific research in a large-scale user facility like the MagLab.

September 11, 2023

A specialized cybersecurity approach was developed to meet the needs of a user research facility.


(A) Broadband 21 T FT-ICR mass spectrum of Suwanee River Fulvic Acid, a Natural Organic Matter reference standard.  (B) Mass-scale zoom inset that highlights the need for resolving power sufficient to separate species

July 14, 2023

The 21 T FT-ICR mass spectrometer identified four times the number of species in natural organic matter than lower magnetic field systems, providing a…


X-ray crystal structure of normal (KRAS4B)

February 17, 2023

Researchers used the MagLab to produce the first clarified map of KRAS proteins in colon cancer tumors. Twenty-eight additional forms of the KRAS prot…


Coal tar pavement sealant contains 50,000 to 75,000 ppm of carcinogenic polycyclic aromatic hydrocarbons (PAHs). Weathering by sunlight and rain can contaminate natural waterways through oxidation of the PAHs contained in the pavement sealant.

October 18, 2022

New research shows that high concentrations of polycyclic aromatic hydrocarbons (PAHs) found in coal tar pavement sealants are oxidized into toxic, wa…


Network diagram suggesting the presence of sulfur-containing (black) PFAS chemicals with a range of perfluoroalkyl (CF2, blue) and ethoxy (C2H4O, orange) chain lengths.

July 18, 2022

Using the world's most powerful mass spectrometer, scientists have developed a new method to profile complex PFAS mixtures at the molecular level, fac…


The Human Proteoform Project separates cell types found in blood.

March 11, 2022

A new Blood Proteoform Atlas maps 30,000 unique proteoforms as they appear in 21 different cell types found in human blood. The MagLab's 21 tesla FT-I…


Sunlight breaks down plastics, creating thousands of compounds whose environmental impact is not understood.

October 25, 2021

Sunlight can chemically transform plastics from consumer plastic bags into complex chemical mixtures that leach into the ocean. Understanding the impa…


Map of the drainage basins of six Arctic rivers, with water sampling points shown in red

June 23, 2021

Researchers share new insights on the role of seasonality in dissolved organic matter (DOM) composition in large Arctic rivers. Researchers share new …


Novel unique molecular forms of proteins - aka proteoforms - were discovered in cancer cells when researchers reanalyzed data from the ICR facility's 21T FT-ICR instrument (right) with new software (left; figure adapted from Wenrong Chen and Xiaowen Liu. Proteoform Identification by Combining RNA-Seq and Top-Down Mass Spectrometry. Journal of Proteome Research, 2021, vol. 20, pp. 261-269)

June 10, 2021

Reuse of the MagLab's Ion Cyclotron Resonance facility data improved understanding of protein fragmentation and aided the design and release of new al…


Relative abundances of water-soluble oxygen-containing compounds, where Ox on the horizontal axis denotes the summed abundances of all compounds containing x oxygen atoms. Data are shown after 24, 72, and 168 hours of simulated sunlight irradiation of road asphalt binder.

March 29, 2021

Road asphalt is made from aggregate (rocks) mixed with a "binder” from the residue remaining after extraction of gasoline and oils from petroleum crud…


1. Patients with multiple myeloma produce different antibodies, depending on which cells are cancerous. 2. Scientists use FT-ICR MS/MS to examine the antibodies. 3. They can tell exactly which antibodies a patient is producing. 4. This knowledge allows them to personalize treatment for each patient.

August 09, 2017

New technique could lead to precise, personalized cancer diagnosis and monitoring.